FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
5-Amino-1MQ Wholesale
Small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor — supplied as a research reagent, not a peptide
Product Identity
| CAS Number | 42464-96-0 |
| Molecular Formula | C₁₀H₁₁IN₂ |
| Molecular Weight | ~286.1 Da |
| Appearance | White to off-white powder |
| Purity | ≥99% by HPLC |
| Solubility | Soluble in water or aqueous buffer |
| Storage | 2–8°C, desiccated, protect from light |
| Identification | ESI-MS identity confirmation on each batch |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 5 mg × 10 vials | Protocol validation; evaluation orders |
| Bulk Kit | 50 mg × 10 vials | High-throughput research; repeat buyers |
| Custom | Custom mg × custom vials | OEM; private-label; protocol-specific |
Research Background
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that consumes methyl groups and NAD+ precursors. It is used in cell and animal research models investigating adipocyte lipid handling, NAD+ availability and NNMT-dependent methylation flux. Because it is not a peptide, it is supplied as a powder for laboratory reconstitution rather than as a lyophilized peptide vial standard.
Proposed Mechanisms
Research Focus Areas
NNMT-dependent NAD+ flux in cultured cells
Lipid accumulation and differentiation models
Chemical probes for methylation-flux research
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity | ESI-MS | Da |
| Appearance | Visual inspection | White to off-white powder |
| Purity assay | Amino acid analysis | ≥80% net peptide |
| Residual moisture | Karl Fischer | ≤3% |
| Solubility | Reconstitution test | Soluble in water or aqueous buffer |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 5 mg × 10 vials | 5AM | US$53 |
| 10 mg × 10 vials | 10AM | US$113 |
| 50 mg × 10 vials | 50AM | US$130 |
US$53–130 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
What is 5-Amino-1MQ and is it a peptide?
5-Amino-1MQ is a small-molecule quinolinium iodide salt (CAS 42464-96-0), not a peptide. It is a nicotinamide N-methyltransferase (NNMT) inhibitor used as a laboratory research reagent.
What purity is supplied?
≥99% by HPLC, with identity confirmed by mass spectrometry. A batch-specific Certificate of Analysis accompanies every kit.
How is 5-Amino-1MQ supplied and stored?
Supplied as a powder in 10-vial kits. Store sealed, desiccated at 2–8°C, protected from light. Reconstitution solvent depends on your protocol; the COA states the batch solubility result.
Is a COA provided?
Yes — a batch-specific COA with HPLC purity and MS identity data ships with every order. Full chromatograms are available on request.
All products are manufactured for laboratory research purposes only. 5-Amino-1MQ is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.
Ready to Source 5-Amino-1MQ?
Bulk pricing, tiered discounts up to 30%, COA with every order.