FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
MOTS-c Wholesale
Mitochondrial-derived peptide (16 aa) studied in metabolic-homeostasis and AMPK-pathway research
Product Identity
| CAS Number | 1627580-64-6 |
| Molecular Formula | C₁₀₁H₁₅₂N₂₈O₂₂S₂ |
| Molecular Weight | ~2,174.6 Da |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% by HPLC |
| Solubility | Soluble in sterile water or PBS |
| Storage | 2–8°C, desiccated, protect from light |
| Identification | ESI-MS identity confirmation on each batch |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 10 mg × 10 vials | Protocol validation; evaluation orders |
| Bulk Kit | 40 mg × 10 vials | High-throughput research; repeat buyers |
| Custom | Custom mg × custom vials | OEM; private-label; protocol-specific |
Research Background
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA. Published research describes its role in metabolic homeostasis — notably AMPK-pathway signalling, the folate–methionine cycle and muscle insulin-sensitivity models — which is why it is widely used alongside nuclear-encoded peptides in mitochondrial and metabolic research.
Proposed Mechanisms
Research Focus Areas
Retrograde signalling from mitochondrial DNA-encoded peptides
Muscle glucose handling and energy metabolism models
Exercise-mimetic and metabolic-adaptation studies
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity | ESI-MS | Da |
| Appearance | Visual inspection | White to off-white lyophilized powder |
| Purity assay | Amino acid analysis | ≥80% net peptide |
| Residual moisture | Karl Fischer | ≤3% |
| Solubility | Reconstitution test | Soluble in sterile water or PBS |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 10 mg × 10 vials | MS10 | US$66 |
| 20 mg × 10 vials | MS20 | US$115 |
| 40 mg × 10 vials | MS40 | US$193 |
US$66–193 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
What is MOTS-c?
MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial 12S rRNA region (CAS 1627580-64-6). Research interest centres on its role in metabolic homeostasis and AMPK-pathway signalling.
How does MOTS-c differ from other metabolic peptides in your catalogue?
Unlike GLP-1 receptor agonists such as Semaglutide, MOTS-c is not a GPCR agonist — it is a mitochondrial-derived peptide studied for intracellular metabolic signalling, so the two are used in different research designs.
Is MOTS-c sequence and identity documented?
Yes: CAS, molecular formula and molecular weight are stated on the product page and in the downloadable dataset; batch identity is confirmed by mass spectrometry on each COA.
What are your kit sizes and pricing tiers?
10 mg, 20 mg and 40 mg × 10-vial kits; volume discounts of 10% (5+ kits), 20% (20+) and 30% (50+).
All products are manufactured for laboratory research purposes only. MOTS-c is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.
Ready to Source MOTS-c?
Bulk pricing, tiered discounts up to 30%, COA with every order.