FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
IGF-1 LR3 Wholesale
Recombinant long R3 IGF-1 analogue with reduced IGFBP affinity for cell-culture and IGF-1R signalling research
Product Identity
| CAS Number | Not fixed in catalogue — confirmed on batch COA |
| Molecular Formula | Recombinant 83-amino-acid analogue — composition per COA |
| Molecular Weight | Mass confirmed per batch COA |
| Amino Acids | 83 (long R3 analogue) |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥95% by HPLC (recombinant protein) |
| Storage | −20°C long term, desiccated, protect from light |
| Identification | Mass confirmation on each batch COA |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 10 mg × 10 vials | Protocol validation; evaluation orders |
| Bulk Kit | 40 mg × 10 vials | High-throughput research; repeat buyers |
| Custom | Custom mg × custom vials | OEM; private-label; protocol-specific |
Research Background
IGF-1 LR3 is a recombinant analogue of insulin-like growth factor 1: an 83-amino-acid single-chain protein carrying an N-terminal extension and an arginine substitution at position 3. The modification reduces affinity for IGF-binding proteins, which is why it is preferred over native IGF-1 in cell-culture and receptor-signalling experiments where free-ligand availability matters. Because it is a recombinant protein rather than a synthetic peptide, identity and mass are confirmed batch by batch.
Proposed Mechanisms
Research Focus Areas
Myoblast proliferation and differentiation models
Receptor-level and downstream pathway research
Serum-free media supplementation and growth-factor studies
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity | ESI-MS | Da |
| Appearance | Visual inspection | White to off-white lyophilized powder |
| Purity assay | Amino acid analysis | ≥80% net peptide |
| Residual moisture | Karl Fischer | ≤3% |
| Solubility | Reconstitution test | Soluble in sterile water or PBS |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 0.1 mg × 10 vials | IG01 | US$42 |
US$42–42 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
Why is no fixed CAS number listed for IGF-1 LR3?
It is a recombinant protein rather than a small synthetic molecule, so identity is established batch by batch through mass confirmation and reported on the COA instead of being quoted as a fixed catalogue CAS number.
How is IGF-1 LR3 different from native IGF-1?
The LR3 analogue carries an N-terminal extension and an arginine substitution at position 3, which reduces affinity for IGF-binding proteins and increases the fraction of free ligand available in culture systems.
What is the purity specification?
Recombinant proteins in this catalogue are specified as ≥95% by HPLC, with the actual value for your lot printed on the Certificate of Analysis.
How should the lyophilized protein be stored?
Store the lyophilized powder desiccated at −20 °C for long-term stability, protected from light; avoid repeated freeze–thaw cycles of reconstituted solution.
What kit sizes are available?
IGF-1 LR3 is supplied as 0.1 mg × 10 vials, with tiered wholesale discounts from 10% at 5+ kits to 30% at 50+ kits and custom configurations for OEM projects.
All products are manufactured for laboratory research purposes only. MOTS-c is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.
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Bulk pricing, tiered discounts up to 30%, COA with every order.