FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
KPV Wholesale
C-terminal α-MSH tripeptide fragment (Lys-Pro-Val) for inflammation-pathway research
Product Identity
| CAS Number | 67727-97-3 |
| Molecular Formula | C₁₆H₃₀N₄O₄ |
| Molecular Weight | ~342.4 Da |
| Sequence | H-Lys-Pro-Val-OH |
| Amino Acids | 3 (tripeptide) |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% by HPLC |
| Solubility | Soluble in sterile water or PBS |
| Storage | 2–8°C, desiccated, protect from light |
| Identification | ESI-MS identity confirmation on each batch |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 5 mg × 10 vials | Protocol validation; evaluation orders |
| Bulk Kit | 10 mg × 10 vials | High-throughput research; repeat buyers |
| Custom | Custom mg × custom vials | OEM; private-label; protocol-specific |
Research Background
KPV is the C-terminal tripeptide fragment of α-melanocyte-stimulating hormone (Lys-Pro-Val). Research on this fragment has focused on melanocortin-linked anti-inflammatory signalling in cell and animal models, where it is studied separately from the full-length hormone because it retains a distinct activity profile without the pigmentation-associated receptor activity of the intact peptide.
Proposed Mechanisms
Research Focus Areas
NF-κB and cytokine-signalling models
Intestinal epithelial in vitro models
Structure–activity studies of α-MSH fragments
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity | ESI-MS | Da |
| Appearance | Visual inspection | White to off-white lyophilized powder |
| Purity assay | Amino acid analysis | ≥80% net peptide |
| Residual moisture | Karl Fischer | ≤3% |
| Solubility | Reconstitution test | Soluble in sterile water or PBS |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 5 mg × 10 vials | KP5 | US$53 |
| 10 mg × 10 vials | KP10 | US$66 |
US$53–66 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
What is KPV?
KPV is the tripeptide Lys-Pro-Val (CAS 67727-97-3), the C-terminal fragment of α-melanocyte-stimulating hormone, used as a research reagent in inflammation-pathway studies.
How does KPV differ from full-length α-MSH?
KPV is a three-residue fragment rather than the full hormone, and research focuses on its inflammatory-signalling profile rather than the pigmentation-associated melanocortin activity of the intact peptide.
What kit configurations are available?
5 mg and 10 mg × 10-vial kits, plus custom vial sizes for OEM and protocol-specific work.
Which documentation is supplied?
A batch-specific COA with HPLC purity and MS identity, plus invoice and packing list. Full chromatograms on request.
All products are manufactured for laboratory research purposes only. KPV is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.