FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
Thymosin Alpha-1 Wholesale
Synthetic 28-residue thymosin α1 — an immune-modulation research peptide
Product Identity
| CAS Number | 62304-98-7 |
| Molecular Formula | C₁₂₉H₂₁₅N₃₃O₅₅ |
| Molecular Weight | ~3,108.3 Da |
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH (residues 2–29 of human prothymosin α, UniProt P06454) |
| Amino Acids | 28 |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% by HPLC |
| Solubility | Soluble in sterile water or PBS |
| Storage | 2–8°C, desiccated, protect from light |
| Identification | ESI-MS identity confirmation on each batch |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 5 mg × 10 vials | Protocol validation; evaluation orders |
| Bulk Kit | 10 mg × 10 vials | High-throughput research; repeat buyers |
| Custom | Custom mg × custom vials | OEM; private-label; protocol-specific |
Research Background
Thymosin α1 is a 28-amino-acid peptide corresponding to the N-terminal region of prothymosin α, supplied here as the synthetic, N-terminally acetylated peptide. It is one of the most extensively characterised immune-modulating peptides and is used in immunology research models studying T-cell maturation and innate-immune signalling endpoints.
Proposed Mechanisms
Research Focus Areas
T-cell development and activation models
TLR-pathway signalling studies
Immune-cell cytokine profiling
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity | ESI-MS | Da |
| Appearance | Visual inspection | White to off-white lyophilized powder |
| Purity assay | Amino acid analysis | ≥80% net peptide |
| Residual moisture | Karl Fischer | ≤3% |
| Solubility | Reconstitution test | Soluble in sterile water or PBS |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 5 mg × 10 vials | TA5 | US$93 |
| 10 mg × 10 vials | TA10 | US$172 |
US$93–172 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
What is Thymosin Alpha-1?
It is a synthetic 28-amino-acid peptide corresponding to residues 2–29 of human prothymosin α (CAS 62304-98-7), used as a research reagent in immunology.
Is the sequence documented?
Yes — the product page states the sequence and precursor reference (UniProt P06454), and each batch is identity-confirmed by mass spectrometry.
What is the difference between Thymosin Alpha-1 and TB-500?
They are unrelated peptides that both derive from larger precursor proteins: thymosin α1 comes from prothymosin α and is studied in immune signalling, whereas TB-500 (thymosin β4 fragment) is studied in actin-sequestration and cell-migration models.
How is it stored and shipped?
Shipped as lyophilized powder in 10-vial kits; store desiccated at 2–8°C protected from light, and aliquot after reconstitution to avoid freeze–thaw cycles.
All products are manufactured for laboratory research purposes only. Thymosin Alpha-1 is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.
Ready to Source Thymosin Alpha-1?
Bulk pricing, tiered discounts up to 30%, COA with every order.