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FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →

Thymosin Alpha-1 Wholesale

Synthetic 28-residue thymosin α1 — an immune-modulation research peptide

Product Identity

CAS Number62304-98-7
Molecular FormulaC₁₂₉H₂₁₅N₃₃O₅₅
Molecular Weight~3,108.3 Da
SequenceAc-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH (residues 2–29 of human prothymosin α, UniProt P06454)
Amino Acids28
AppearanceWhite to off-white lyophilized powder
Purity≥99% by HPLC
SolubilitySoluble in sterile water or PBS
Storage2–8°C, desiccated, protect from light
IdentificationESI-MS identity confirmation on each batch

Available Configurations

ConfigurationContentBest For
Standard Kit5 mg × 10 vialsProtocol validation; evaluation orders
Bulk Kit10 mg × 10 vialsHigh-throughput research; repeat buyers
CustomCustom mg × custom vialsOEM; private-label; protocol-specific

Research Background

Thymosin α1 is a 28-amino-acid peptide corresponding to the N-terminal region of prothymosin α, supplied here as the synthetic, N-terminally acetylated peptide. It is one of the most extensively characterised immune-modulating peptides and is used in immunology research models studying T-cell maturation and innate-immune signalling endpoints.

Proposed Mechanisms

T-cell maturation researchStudied in models of thymocyte and T-cell development
Innate immune signallingReported effects on Toll-like receptor-dependent signalling pathways in cell models
Dendritic cell researchInvestigated in antigen-presenting cell models

Research Focus Areas

Immunology Research

T-cell development and activation models

Innate Immunity

TLR-pathway signalling studies

Cytokine Research

Immune-cell cytokine profiling

Quality Specifications

ParameterMethodCriterion
PurityHPLC at 214 nm, C18 column≥99.0% peak area
IdentityESI-MSDa
AppearanceVisual inspectionWhite to off-white lyophilized powder
Purity assayAmino acid analysis≥80% net peptide
Residual moistureKarl Fischer≤3%
SolubilityReconstitution testSoluble in sterile water or PBS

Tiered Wholesale Pricing

Kit sizeCodeList price
5 mg × 10 vialsTA5US$93
10 mg × 10 vialsTA10US$172

US$93–172 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).

VolumeDiscountFor
1 kitList priceEvaluation; competitive analysis
5+ kits10% offInitial portfolio expansion
20+ kits20% offMid-size distributors
50+ kits30% offRegional distributors

FAQ

What is Thymosin Alpha-1?

It is a synthetic 28-amino-acid peptide corresponding to residues 2–29 of human prothymosin α (CAS 62304-98-7), used as a research reagent in immunology.

Is the sequence documented?

Yes — the product page states the sequence and precursor reference (UniProt P06454), and each batch is identity-confirmed by mass spectrometry.

What is the difference between Thymosin Alpha-1 and TB-500?

They are unrelated peptides that both derive from larger precursor proteins: thymosin α1 comes from prothymosin α and is studied in immune signalling, whereas TB-500 (thymosin β4 fragment) is studied in actin-sequestration and cell-migration models.

How is it stored and shipped?

Shipped as lyophilized powder in 10-vial kits; store desiccated at 2–8°C protected from light, and aliquot after reconstitution to avoid freeze–thaw cycles.

All products are manufactured for laboratory research purposes only. Thymosin Alpha-1 is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.

Ready to Source Thymosin Alpha-1?

Bulk pricing, tiered discounts up to 30%, COA with every order.

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