FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
SS-31 (Elamipretide) Wholesale
Mitochondria-targeted tetrapeptide (elamipretide) — cardiolipin-binding research peptide
Product Identity
| CAS Number | 736992-21-5 |
| Molecular Formula | C₃₂H₄₉N₉O₅ |
| Molecular Weight | ~639.8 Da |
| Amino Acids | 4 (tetrapeptide, D-amino-acid and 2',6'-dimethyltyrosine containing) |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% by HPLC |
| Solubility | Soluble in sterile water or PBS |
| Storage | 2–8°C, desiccated, protect from light |
| Identification | ESI-MS identity confirmation on each batch |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 10 mg × 10 vials | Protocol validation; evaluation orders |
| Bulk Kit | 50 mg × 10 vials | High-throughput research; repeat buyers |
| Custom | Custom mg × custom vials | OEM; private-label; protocol-specific |
Research Background
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide containing D-arginine and 2′,6′-dimethyltyrosine. Its design gives it affinity for cardiolipin on the inner mitochondrial membrane, and it is one of the most-cited tool peptides in mitochondrial-dysfunction and bioenergetics research, where it is used to probe electron-transport-chain efficiency and reactive-oxygen-species endpoints in cell and animal models.
Proposed Mechanisms
Research Focus Areas
Bioenergetics and respiratory-chain research
Mitochondrial ROS endpoint studies
Mitochondrial-pathway apoptosis models
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity | ESI-MS | Da |
| Appearance | Visual inspection | White to off-white lyophilized powder |
| Purity assay | Amino acid analysis | ≥80% net peptide |
| Residual moisture | Karl Fischer | ≤3% |
| Solubility | Reconstitution test | Soluble in sterile water or PBS |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 10 mg × 10 vials | 2S10 | US$79 |
| 50 mg × 10 vials | 2S50 | US$291 |
US$79–291 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
What is SS-31?
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide, CAS 736992-21-5, used as a research reagent in mitochondrial-biology studies.
Why does SS-31 contain D-amino acids?
The D-arginine and dimethyltyrosine residues improve metabolic stability and give the peptide its cardiolipin-binding character, which is why it is used as a targeted mitochondrial tool rather than a signalling peptide.
How does SS-31 differ from MOTS-c?
Both are studied in mitochondrial research, but MOTS-c is a mitochondrial-DNA-encoded 16-residue peptide studied for metabolic signalling, while SS-31 is a synthetic, cell-penetrating tetrapeptide that binds cardiolipin.
Which kit sizes and pricing are available?
10 mg and 50 mg × 10-vial kits, on the published price list, with volume discounts from 5 kits.
All products are manufactured for laboratory research purposes only. SS-31 is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.
Ready to Source SS-31?
Bulk pricing, tiered discounts up to 30%, COA with every order.