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FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →

HGH Wholesale

Human Growth Hormone (somatropin) — 191-amino acid central regulator of the GH/IGF-1 axis, batch-documented, manufacturer-direct

Product Identity

CAS Number12629-01-5
Sequence191-amino acid polypeptide with 2 disulfide bonds (Cys⁵³-Cys¹⁶⁵, Cys¹⁸²-Cys¹⁸⁹)
Molecular FormulaC₉₉₀H₁₅₂₈N₂₆₂O₃₀₀S₇
Molecular Weight~22,125 Da
Isoelectric Point~5.2
AppearanceWhite to off-white lyophilized powder
Purity≥99% by HPLC
SolubilitySterile water or bacteriostatic water; gentle swirling
Storage2–8°C (lyophilized); use promptly after reconstitution

Available Configurations

ConfigurationContentBest For
100 IU Kit10 IU (~3.3mg) × 10 vialsEvaluation; small-scale research
150 IU Kit15 IU (~5mg) × 10 vialsMedium-scale protocols
200 IU Kit20 IU (~6.7mg) × 10 vialsHigh-throughput; bulk research
CustomCustom IU × custom vialsOEM; specific protocols

Research Background

Human Growth Hormone is a 191-amino acid, single-chain polypeptide synthesized by somatotroph cells in the anterior pituitary. It is the primary regulator of postnatal somatic growth and a key metabolic hormone — controlling the GH/IGF-1 axis via hypothalamic GHRH (+) and somatostatin (-) regulation.

Proposed Mechanisms

JAK-STAT SignalingGH→GHR dimerization→JAK2→STAT5→IGF-1 transcription
IGF-1 CascadeHepatic IGF-1 production → systemic anabolic and growth effects
LipolysisDirect GH receptor activation on adipocytes → enhanced fat mobilization
Protein SynthesisGH + IGF-1 → amino acid uptake and protein synthesis in skeletal muscle

Research Focus Areas

Body Composition

GH effects on lean mass, fat mass, bone density

Muscle Protein

Anabolic signaling; fractional synthetic rate

Aging Research

Age-related GH decline (somatopause); IGF-1 models

Metabolism

Lipolytic effects; insulin sensitivity modulation

Recovery & Repair

GH effects on tissue repair; collagen synthesis

Quality Specifications

ParameterMethodCriterion
Purity (HPLC)RP-HPLC, C18≥99.0% peak area
Identity (MW)ESI-MS / MALDI-TOF~22,125 ± 5.0 Da
AppearanceVisualWhite to off-white powder
Protein ContentUV A₂₈₀ / Bradford≥90% of labeled content
Purity (SDS-PAGE)Reducing SDS-PAGESingle band at ~22 kDa (bulk orders)
Residual MoistureKarl Fischer≤3%
EndotoxinLAL assay≤1.0 EU/mg (on request)

Tiered Wholesale Pricing

Kit prices are quoted per specification — current list prices for peptide kits run from US$24 to US$339 per kit (10 vials); tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).

VolumeDiscountFor
1 kitList priceEvaluation; competitive analysis
5+ kits10% offInitial portfolio expansion
20+ kits20% offMid-size distributors
50+ kits30% offRegional distributors

FAQ

What's the difference between HGH and GHS peptides (CJC-1295, Ipamorelin)?

HGH directly activates GH receptors on target tissues and stimulates IGF-1. GHS peptides (CJC-1295, Ipamorelin) stimulate pituitary release of endogenous GH. For direct GH receptor studies: use HGH. For GH axis regulation studies: use GHS peptides. In body composition research, HGH gives precise dose control; GHS peptides produce more physiological but less controllable responses.

How should HGH be reconstituted and stored?

Reconstitute with sterile or bacteriostatic water — add diluent gently down vial wall, don't squirt onto powder. Swirl gently (never shake or vortex — denatures protein). Store reconstituted at 2–8°C, use within 7–14 days. Never freeze-thaw — causes aggregation and bioactivity loss.

Which kit size should I order?

Rodent research: 100 IU kit (10 IU vials) for weight-based dosing. Larger animal models or high-concentration cell culture: 150 IU or 200 IU kits. Uncertain? Start with 100 IU evaluation. Contact us — share your model and we'll recommend the right configuration.

How do you verify it's actually intact HGH and not a fragment?

Three methods: (1) Mass spectrometry confirms MW ~22,125 Da ±5 Da — a fragment would show different mass. (2) SDS-PAGE shows single band at ~22 kDa — multiple bands = impurities or degradation. (3) RP-HPLC confirms ≥99% single-peak purity. All three in our QC release testing for research-grade HGH.

All products are manufactured for laboratory research purposes only. HGH is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country. HGH is a controlled or prescription-only substance in many jurisdictions — buyers must hold any licence required to import or possess it.

Ready to Source HGH?

Three kit configurations. Tiered pricing up to 30%. Full analytical QC: MS + SDS-PAGE + HPLC with every bulk order.

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