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FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →

Sermorelin Wholesale

GHRH(1-29) analogue — the standard GHRH-receptor research peptide for GH-axis models

Product Identity

CAS Number86168-78-7
Molecular FormulaC₁₄₉H₂₄₆N₄₄O₄₂S
Molecular Weight~3,357.9 Da
Amino Acids29
AppearanceWhite to off-white lyophilized powder
Purity≥99% by HPLC
SolubilitySoluble in sterile water or PBS
Storage2–8°C, desiccated, protect from light
IdentificationESI-MS identity confirmation on each batch

Available Configurations

ConfigurationContentBest For
Standard Kit5 mg × 10 vialsProtocol validation; evaluation orders
Bulk Kit10 mg × 10 vialsHigh-throughput research; repeat buyers
CustomCustom mg × custom vialsOEM; private-label; protocol-specific

Research Background

Sermorelin is the 29-amino-acid N-terminal fragment of growth-hormone-releasing hormone, GHRH(1-29), and corresponds to the shortest sequence that retains full GHRH-receptor activity. Because GHRH acts at the pituitary receptor rather than the ghrelin receptor, sermorelin is the classic comparator in research contrasting GHRH-receptor with ghrelin-receptor secretagogue signalling.

Proposed Mechanisms

GHRH-receptor agonismDirect pituitary GHRH-receptor activation studied in GH-axis research models
cAMP/PKA signallingGHRH receptor signals through Gs-coupled cAMP pathways in somatotroph models
Receptor-class comparisonBenchmark for distinguishing GHRH-receptor from ghrelin-receptor secretagogues

Research Focus Areas

GH-Axis Research

Pituitary somatotroph signalling models

Receptor Pharmacology

GHRH-receptor vs ghrelin-receptor comparisons

Secretagogue Characterisation

Structure–activity studies of GHRH fragments

Quality Specifications

ParameterMethodCriterion
PurityHPLC at 214 nm, C18 column≥99.0% peak area
IdentityESI-MSDa
AppearanceVisual inspectionWhite to off-white lyophilized powder
Purity assayAmino acid analysis≥80% net peptide
Residual moistureKarl Fischer≤3%
SolubilityReconstitution testSoluble in sterile water or PBS

Tiered Wholesale Pricing

Kit sizeCodeList price
5 mg × 10 vialsSMO5US$69
10 mg × 10 vialsSMO10US$106

US$69–106 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).

VolumeDiscountFor
1 kitList priceEvaluation; competitive analysis
5+ kits10% offInitial portfolio expansion
20+ kits20% offMid-size distributors
50+ kits30% offRegional distributors

FAQ

What is Sermorelin?

Sermorelin is the GHRH(1-29) fragment (CAS 86168-78-7), a 29-amino-acid peptide and the classic GHRH-receptor agonist used in growth-hormone-axis research.

How does Sermorelin differ from Ipamorelin or GHRP-2?

Sermorelin acts on the GHRH receptor. Ipamorelin, GHRP-2 and GHRP-6 act on the ghrelin receptor. Research designs comparing the two classes test different upstream signalling routes to GH release.

Which kit sizes are stocked?

5 mg and 10 mg × 10-vial kits; custom configurations on request.

What documentation ships with the order?

Batch-specific COA (HPLC purity, MS identity), commercial invoice and packing list; full spectra on request.

All products are manufactured for laboratory research purposes only. Sermorelin is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.

Ready to Source Sermorelin?

Bulk pricing, tiered discounts up to 30%, COA with every order.

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