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FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →

Tesamorelin Wholesale

Stabilised GHRH(1-44) analogue — long-acting GHRH-receptor agonist for GH-axis research

Product Identity

CAS Number218949-48-5
Molecular FormulaC₂₂₁H₃₆₆N₇₂O₆₇S
Molecular Weight~5,136 Da
Amino Acids44
AppearanceWhite to off-white lyophilized powder
Purity≥99% by HPLC
SolubilitySoluble in sterile water or PBS
Storage2–8°C, desiccated, protect from light
IdentificationESI-MS identity confirmation on each batch

Available Configurations

ConfigurationContentBest For
Standard Kit5 mg × 10 vialsProtocol validation; evaluation orders
Bulk Kit20 mg × 10 vialsHigh-throughput research; repeat buyers
CustomCustom mg × custom vialsOEM; private-label; protocol-specific

Research Background

Tesamorelin is a 44-amino-acid GHRH analogue: the full-length GHRH(1-44) sequence with a trans-3-hexenoyl modification at the N-terminus that increases resistance to DPP-IV cleavage. That stability difference is the reason it is used in GH-axis research where a longer-acting GHRH-receptor stimulus is required, as distinct from the shorter GHRH(1-29) analogue Sermorelin.

Proposed Mechanisms

GHRH-receptor agonismFull-length GHRH-receptor activation studied in pituitary somatotroph models
Enhanced stabilityN-terminal acylation reduces DPP-IV-mediated degradation relative to unmodified GHRH
GH-axis endpointsResearch on pulsatile GH release and downstream IGF-1-axis markers in animal models

Research Focus Areas

GH-Axis Research

Long-acting GHRH-receptor stimulation models

Peptide Stability Engineering

DPP-IV resistance in GHRH analogue design

Comparative Pharmacology

GHRH(1-29) vs GHRH(1-44) analogue studies

Quality Specifications

ParameterMethodCriterion
PurityHPLC at 214 nm, C18 column≥99.0% peak area
IdentityESI-MSDa
AppearanceVisual inspectionWhite to off-white lyophilized powder
Purity assayAmino acid analysis≥80% net peptide
Residual moistureKarl Fischer≤3%
SolubilityReconstitution testSoluble in sterile water or PBS

Tiered Wholesale Pricing

Kit sizeCodeList price
5 mg × 10 vialsTSM5US$111
10 mg × 10 vialsTSM10US$185
20 mg × 10 vialsTSM20US$339

US$111–339 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).

VolumeDiscountFor
1 kitList priceEvaluation; competitive analysis
5+ kits10% offInitial portfolio expansion
20+ kits20% offMid-size distributors
50+ kits30% offRegional distributors

FAQ

What is Tesamorelin?

Tesamorelin (CAS 218949-48-5) is a stabilised GHRH(1-44) analogue used as a research reagent in growth-hormone-axis studies.

How does it differ from Sermorelin?

Sermorelin is GHRH(1-29); Tesamorelin is the full-length GHRH(1-44) with an N-terminal modification that slows enzymatic degradation, so research designs differ in the duration of receptor stimulation.

Which kit sizes are available?

5 mg, 10 mg and 20 mg × 10-vial kits — the widest configuration range in our GH-axis portfolio.

Do you supply research documentation?

Yes: batch-specific COA, and MS/HPLC data on request. Our documentation is analytical, not regulatory — these are research reagents.

All products are manufactured for laboratory research purposes only. Tesamorelin is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.

Ready to Source Tesamorelin?

Bulk pricing, tiered discounts up to 30%, COA with every order.

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