FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
Ipamorelin Wholesale
Selective ghrelin receptor (GHS-R1a) agonist — minimal hunger signaling, clean GH pulse, manufacturer-direct
Product Identity
| CAS Number | 170851-70-4 |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH₂ |
| Amino Acids | 5 (Aib¹, D-2-Nal³, D-Phe⁴ modified) |
| Molecular Formula | C₃₈H₄₉N₉O₅ |
| Molecular Weight | ~711.9 Da |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% by HPLC |
| Solubility | Soluble in sterile or bacteriostatic water |
| Storage | 2–8°C, desiccated, protect from light |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 2 mg × 10 vials | GH pulse studies; evaluation |
| Bulk Kit | 5 mg × 10 vials | Chronic protocols; repeat orders |
| Custom | Custom mg × custom vials | OEM; private-label |
Research Background
Ipamorelin is a synthetic pentapeptide GH secretagogue that selectively activates the ghrelin receptor (GHS-R1a). What distinguishes it from earlier GHS peptides is receptor selectivity — it produces a clean GH pulse with minimal activation of ACTH/cortisol, prolactin, or hunger-signaling pathways. This selectivity is achieved through strategic incorporation of non-proteinogenic amino acids: Aib at position 1, D-2-Nal at position 3, and D-Phe at position 4.
Proposed Mechanisms
Research Focus Areas
Clean GH pulse with minimal prolactin, ACTH, or cortisol elevation
GHS-R1a pharmacology — receptor selectivity profiling
Lean mass preservation in caloric deficit models
Synergistic GH elevation with GHRH analogues (CJC-1295)
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity (MW) | ESI-MS | ~711.9 ± 1.0 Da |
| Appearance | Visual inspection | White to off-white powder |
| Chiral Purity | Chiral HPLC | ≥99% (Aib, D-2-Nal, D-Phe verified) |
| Residual Moisture | Karl Fischer | ≤3% |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 5 mg × 10 vials | IP5 | US$45 |
| 10 mg × 10 vials | IP10 | US$79 |
| 20 mg × 10 vials | IP20 | US$143 |
US$45–143 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
What makes Ipamorelin different from GHRP-2/GHRP-6?
Selectivity. Ipamorelin is the most selective ghrelin receptor agonist of the GHRP family. At research concentrations, it produces GH release without significant ACTH, cortisol, prolactin, or hunger elevation. GHRP-2/6 are more potent GH releasers but with broader receptor profiles.
Why is Ipamorelin paired with CJC-1295?
CJC-1295 provides the GHRH signal (the 'on' switch). Ipamorelin suppresses somatostatin tone (the 'off' switch). Together they produce synergistic GH pulse — the most studied GH secretagogue protocol in preclinical research.
What are the unique amino acid modifications?
Aib (α-aminoisobutyric acid) at position 1 for protease resistance; D-2-Nal at position 3 for GHS-R binding selectivity; D-Phe at position 4 to further refine selectivity. Confirmed by chiral HPLC in every batch.
How does Ipamorelin affect appetite vs GHRP-6?
Minimally. GHRP-6 is a potent ghrelin mimetic that strongly activates hunger signaling. Ipamorelin was specifically designed to reduce this off-target effect while maintaining GH release.
What purity and QC documentation is provided?
≥99% HPLC purity, ESI-MS identity, and chiral HPLC verification of D-amino acid content. Batch-specific COA included.
All products are manufactured for laboratory research purposes only. Ipamorelin is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.
Ready to Source Ipamorelin?
Bulk pricing, tiered discounts up to 30%, COA with every order.