FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
GHRP-2 Wholesale
Growth Hormone Releasing Peptide-2 — potent ghrelin mimetic for GH pulse research, manufacturer-direct
Product Identity
| CAS Number | 158861-67-7 |
| Sequence | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂ |
| Amino Acids | 6 (D-Ala¹, D-2-Nal², D-Phe⁵) |
| Molecular Formula | C₄₅H₅₅N₉O₆ |
| Molecular Weight | ~817.0 Da |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% by HPLC |
| Solubility | Soluble in sterile or bacteriostatic water |
| Storage | 2–8°C, desiccated, protect from light |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 5 mg × 10 vials | GH pulse research; evaluation |
| Bulk Kit | 10 mg × 10 vials | Chronic protocols; repeat orders |
| Custom | Custom mg × custom vials | OEM; private-label |
Research Background
GHRP-2 (also known as Pralmorelin) is a synthetic hexapeptide ghrelin receptor agonist. It is one of the most potent GH secretagogues in the GHRP family, producing a rapid, robust GH pulse. Developed through structure-activity relationship studies of met-enkephalin derivatives, GHRP-2 features D-amino acid modifications (D-Ala¹, D-2-Nal², D-Phe⁵) that confer both metabolic stability and high receptor affinity.
Proposed Mechanisms
Research Focus Areas
Rapid, potent GH release via GHS-R1a activation on pituitary
Sharp GH spikes — compatible with post-exercise window protocols
Ghrelin pathway activation — feeding behavior studies
GH-mediated hepatic IGF-1 production cascade
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity (MW) | ESI-MS | ~817.0 ± 1.0 Da |
| Appearance | Visual inspection | White to off-white powder |
| Chiral Purity | Chiral HPLC | D-amino acids verified |
| Residual Moisture | Karl Fischer | ≤3% |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 5 mg × 10 vials | G25 | US$42 |
US$42–42 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
How potent is GHRP-2 vs other GH secretagogues?
GHRP-2 is among the most potent GHS-R1a agonists, producing GH elevations exceeding GHRP-6 and Ipamorelin at equivalent doses. However, this potency comes with broader receptor profile including stronger appetite stimulation.
What distinguishes GHRP-2 from Ipamorelin?
GHRP-2: more potent GH release, stronger hunger signaling, potential cortisol elevation. Ipamorelin: cleaner GH pulse, minimal hunger, minimal cortisol. Choice depends on whether maximum amplitude or receptor selectivity is the priority.
What is the origin of GHRP-2?
GHRP-2 (Pralmorelin) was developed by Kaken Pharmaceutical in Japan through systematic modification of met-enkephalin derivatives. D-amino acid substitutions provide enzymatic resistance while maintaining high GHS-R1a binding affinity.
How should GHRP-2 be stored?
Lyophilized: 2–8°C, desiccated, 24-month stability. After reconstitution, aliquot and store at -20°C. Avoid freeze-thaw cycles. D-amino acid modifications provide good solution stability.
Can GHRP-2 be combined with CJC-1295?
Yes — common research combination. CJC-1295 provides sustained GHRH signal; GHRP-2 provides potent ghrelin receptor pulse. CJC-1295 (no DAC) + GHRP-2 is particularly suited for pulsatile GH protocol research.
All products are manufactured for laboratory research purposes only. GHRP-2 is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.
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Bulk pricing, tiered discounts up to 30%, COA with every order.