FOR LABORATORY RESEARCH USE ONLY — not for human or veterinary use, diagnosis, treatment, or cosmetic application. Buyers must be 21+ and legally permitted to purchase research chemicals in their jurisdiction.Intended-use statement →
CJC-1295 (no DAC) Wholesale
Short-acting GHRH analogue without Drug Affinity Complex — pulsatile GH research, manufacturer-direct
Product Identity
| CAS Number | 863288-34-0 |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys-NH₂ |
| Amino Acids | 30 (no DAC linker) |
| Molecular Formula | C₁₅₂H₂₅₂N₄₄O₄₂ |
| Molecular Weight | ~3,367.1 Da |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥99% by HPLC |
| Solubility | Soluble in sterile or bacteriostatic water |
| Storage | 2–8°C, desiccated, protect from light |
Available Configurations
| Configuration | Content | Best For |
|---|---|---|
| Standard Kit | 2 mg × 10 vials | Pulsatile GH research; evaluation |
| Bulk Kit | 5 mg × 10 vials | Chronic pulse protocols; repeat orders |
| Custom | Custom mg × custom vials | OEM; private-label |
Research Background
CJC-1295 without DAC (also known as Mod GRF 1-29) is the same 30-amino acid GHRH analogue as the DAC variant, but without the C-terminal maleimidopropionyl linker. This single structural difference produces a fundamentally different pharmacokinetic profile: instead of 8-day sustained GH elevation, the no-DAC variant has a short ~30-minute half-life producing a discrete GH pulse that closely mimics endogenous pulsatile secretion patterns.
Proposed Mechanisms
Research Focus Areas
Physiological GH pulse pattern — short-duration GHRH-R activation
Pulse timing relative to exercise-induced GH window
Paired with GHS-R agonist (Ipamorelin/GHRP-2) for synergistic pulse
Endogenous pulsatile secretion pattern studies
Quality Specifications
| Parameter | Method | Criterion |
|---|---|---|
| Purity | HPLC at 214 nm, C18 column | ≥99.0% peak area |
| Identity (MW) | ESI-MS | ~3,367.1 ± 1.0 Da |
| Appearance | Visual inspection | White to off-white powder |
| Peptide Content | Amino acid analysis | ≥80% net peptide |
| No DAC Confirmation | HPLC-MS | Absence of maleimidopropionyl mass adduct |
Tiered Wholesale Pricing
| Kit size | Code | List price |
|---|---|---|
| 5 mg × 10 vials | CND5 | US$85 |
| 10 mg × 10 vials | CND10 | US$159 |
US$85–159 per kit (10 vials), from our published wholesale price list; tiered volume discounts apply (see the tier table) — source:wholesale price list (PDF, updated 2026-08-08).
| Volume | Discount | For |
|---|---|---|
| 1 kit | List price | Evaluation; competitive analysis |
| 5+ kits | 10% off | Initial portfolio expansion |
| 20+ kits | 20% off | Mid-size distributors |
| 50+ kits | 30% off | Regional distributors |
FAQ
Why choose CJC-1295 without DAC?
Choice depends on research objective. No DAC = ~30 min half-life = discrete physiological GH pulse. With DAC = ~8 day half-life = sustained GH/IGF-1 elevation. Use no DAC for pulsatile GH studies; use DAC for chronic activation.
Is CJC-1295 (no DAC) the same as Mod GRF 1-29?
Essentially yes. Both refer to the same 30-amino acid GHRH analogue with four substitutions but without the DAC linker. Both terms describe the short-acting, non-albumin-binding variant.
What is the optimal partner peptide?
Ipamorelin is preferred for pulsatile protocols: CJC-1295 provides GHRH signal, Ipamorelin suppresses somatostatin tone → synergistic, clean GH pulse. GHRP-2 can be used when maximum pulse amplitude is preferred over selectivity.
What is the half-life difference vs DAC variant?
No DAC: ~30 minutes → discrete GH pulse. With DAC: ~8 days (via albumin conjugation). This ~400-fold difference is entirely due to the maleimidopropionyl DAC linker.
How is absence of DAC verified?
HPLC-MS confirms the molecular ion without the maleimidopropionyl mass adduct (+97 Da absent vs DAC variant). Included in every batch-specific COA.
All products are manufactured for laboratory research purposes only. CJC-1295 (no DAC) is labeled FOR LABORATORY RESEARCH USE ONLY. Not for human or veterinary use, diagnosis, treatment, prophylaxis or any clinical, cosmetic, dietary or household application. Not a dietary supplement, pharmaceutical ingredient, cosmetic ingredient or approved drug substance. Buyers are responsible for verifying the legal status of importation and possession in their destination country.
Ready to Source CJC-1295 (no DAC)?
Bulk pricing, tiered discounts up to 30%, COA with every order.